The simple answer is yes, but, judging from posts on Intuit’s community forums, there’s a lot of confusion on the topic. 1 Most of the initial reports of incompatibility were due to users running a beta version of Microsoft Office 2010, running a 64-bit version of Office 2010, or not having updated QuickBooks to the latest release.
Microsoft Office 2010, like many products, was initially released as a beta version. Intuit generally does not support beta releases. When Microsoft Office 2010 was released as a final product, it offered users the ability to install either a 32-bit or 64-bit version; either version can be installed from the retail Microsoft Office DVD. While the 64-bit version makes more system memory available to applications such as Excel, Microsoft itself cautioned that the 64-bit version is incompatible with many add-ons for Office and recommended that most users install the 32-bit version of Office 2010.
With the 32-bit version of the publicly released Microsoft Office, QuickBooks 2008 (Release 10), 2009 (Release 12), 2010 (Release 9), and 2011 (Release 1) are compatible with Microsoft Office 2010. We’ve tested the basic functionality of using Microsoft Office 2010, such as sending reports with Outlook and exporting to Excel, with each of those QuickBooks versions and observed no problems.
Intuit continues to address compatibility for the 64-bit version of Microsoft Office 2010, as discussed below.
As of the availability of Release 8 for QuickBooks 2010 (released on 9/2/10), QuickBooks 2010 products support some functionality with the 64-bit version of Office 2010, including such popular programs as Outlook 2010, Excel 2010, and Word 2010. However, Intuit points out this functionality is not available in Enterprise Solutions 10.0 or QuickBooks Premier Accountant 2010, an industry-specific version of the QuickBooks Premier product.
Earlier releases of QuickBooks 2010, as well as older versions of QuickBooks, are not compatible with the 64-bit version.
To prepare letters, export reports, synchronize contacts, or send emails (other than using QuickBooks E-mail), QuickBooks 2010 running Release 7 and earlier products support Office 2002, 2003, and 2007.
See our article on how to determine your release of QuickBooks for more information.
For more information, see this Intuit knowledge base article.
[ +2 rating, 2 votes ]
Loading ... 
Looking for discounts on QuickBooks? Check out our
QB2010 is NOT compatible with MS Office 2010 64bit. Don’t believe the snake oil that some try to sell as ‘know it alls’. First hand experience with this issue has driven me nuts and the fact that Intuit gives a **** poor formula to follow to try and help you determine what Office 2010 applications do what with QB 2010 should cause the most dedicated Intuit customer to reconsider using their poor product. http://support.quickbooks.intuit.com/support/pages/knowledgebasearticle/898761#version
Weed
I’m not sure the origin of your snake oil reference, but our article on the subject indicates that there are compatibility problems with the 64 bit version of Office 2010, and Intuit is working to resolve them. Microsoft itself recommends most users install the 32 bit – not the 64 bit – version.